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Posted: 01-May-26
Location: Durham, North Carolina
Categories:
Internal Number: 269516
At Duke Health, we're driven by a commitment to compassionate care that changes the lives of patients, their loved ones, and the greater community. No matter where your talents lie, join us and discover how we can advance health together.
Duke University Health System Clinical Laboratories
Pursue your passion for caring and innovation as a team member in the state-of-the-art Duke Health laboratories. Duke Health laboratories are College of American Pathologists accredited and Clinical Laboratory Improvement Amendments certified. The multidisciplinary team is committed to serving the rare and complex testing needs of Duke Health patients by providing timely and accurate results, educating the next generation of laboratorians, scientists and physicians, and researching and developing the cutting-edge diagnostics of tomorrow.
Medical Lab Scientist, Advanced in the HLA Lab at Duke University Hospital. Monday - Friday, Second Shift.
This position is eligible for the second-shift differential and a $7,500 commitment bonus.
General Description
This position will be responsible for performing, analyzing, and evaluating results for patients receiving solid organ and/or bone marrow transplants. Individuals will work closely with HLA Technical Specialist, Analytical Specialist, and Lab Medical directors to evaluate patient results used in transplant decision making, rejection monitoring, and clinical trials to provide optimal patient outcomes. A strong background in Flow Cytometry, Immunohematology, Immunology, and/or Molecular Biology techniques is preferred.
Work Performed
- Testing performed: HLA Flow PRA screen; Luminex Single Antigen (LSA) HLA Class I & II; Flow cross-matching; ELISA; cell isolation and preservation from peripheral blood and donor tissue specimen; DNA extraction, purification, and quantitation; various molecular typing techniques to include Next-generation sequencing (NGS), RT-PCR, and low to intermediate resolution SSO/SSP typing.
- Participate in equipment maintenance, instrument calibration, quality control and documentation, and monitor reagent inventory.
- Perform sample processing to include cell isolation, preservation, and specimen storage for future testing.
- Organize test worklists, order, and perform necessary sample treatments and/or reflex testing.
- Analyze specimens and evaluate result validity against historical results in conjunction with patient co-morbidities and effect of treatment regimens.
- Serve as a technical resource for less experienced technologist and support staff. Train and mentor other HLA technologist and participate in annual procedure review to articulate procedure/policy changes to ensure SOPs are clearly and concisely worded.
- Participate in quality assurance and quality control data. Uses knowledge of various complex laboratory techniques and procedures to generate quantitative and qualitative observations and initiate problem-solving processes if indicated.
- Position requires limited on-call assignment to include nights, holidays, and weekends on a rotating basis.
Knowledge, Skills and Abilities
Minimum Qualifications
Education
- Bachelor of Science or Bachelor of Arts in Chemical, Physical, Biological, or Clinical Laboratory Science; or Medical Technology.
- Generalist certification required for general laboratories. Generalist or specialty certification required for specialty laboratories.
- Minimum educational or experience requirements may be modified on a case-by-case basis at the discretion of the CLIA Director, provided minimal CLIA requirements are met by the employee for the tasks being performed.
Experience
Two years of experience as a certified MLS.
Degrees, Licensures, Certifications
Generalist or specialty certification by a nationally recognized board or agency (required). Certification will vary depending on laboratory. Master of Science in lieu of certification for the Biochemical Genetics Laboratory.
Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.
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Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.